徐世三  副教授

        研究生招生专业：生化与分子生物学，细胞生物学 

        研究方向：组织再生，药物毒理 

        出生年月：1984年2月

        联系方式：E-mail: perseverancexss@163.com

        通讯地址：广西桂林市育才路15号国重室2号楼 

教育与工作经历

        2013.9–2017.2：香港城市大学生物医学系博士

        2007.9–2010.6：厦门大学华人策略社区硕士

        2003.9–2007.6：三峡大学化学与华人策略社区本科

        2020.12-至今：华人策略社区教师，副教授

        2019.3–2020.12：中银（国际）生物科技有限公司博士后，香港城市大学生物医学系兼职博士后

        2017.2–2019.3：香港城市大学生物医学系博士后

        2011.5–2013.7：水中银（国际）生物科技有限公司高级研究员

教学情况

        本科生课程：《分子生物学》，《分子生物学实验》，《发育生物学》，《生物化学实验》，《生物技术导读》

        研究生课程：《生命科学前沿进展》

科研情况

        目前主持国家自然科学基因一项，参与两项；主持自治区人才专项基金一项；主持校级学科交叉培育项目基金一项。

近年来主要论著

        1. Shisan Xu,Fengyan Chen, Huan Zhang, Zhen-lie Huang, Jianjun Li, Desheng Wu & XuepingChen. Development a high-throughput zebrafish embryo acute toxicity testingmethod based on OECD TG 236. Toxicology Mechanisms and Methods. 2022, 20:1-9.

        2.Fangjing Xie, Shisan Xu*, YingyingLu, Kin Fung Wong, Lei Sun, Kazi Md Mahmudul Hasan, Alvin C H Ma, Gary Tse,Sinai H C Manno, Li Tian, Jianbo Yue, Shuk Han Cheng.Metforminaccelerates zebrafish heart regeneration by inducing autophagy. NPJ RegenMed.. 2021,6(1):62. （*Co-first author）

        3. Shisan Xu,Huan Zhang, Cun-Zhao Li, Ping-Shan Lai, Guijiang Wang, Yu Suen Chan, Shuk HanCheng, Xueping Chen. Cannabidiol promotes fin regeneration and reduces apoptosisin zebrafish embryos. Journal of Functional Foods. 2021,86:104694.

        4. Shisan Xu,Huan Zhang, Ping-Chieh Pao, Audrey Lee, Jun Wang, Yu Suen Chan, Francis A. M.Manno III, Shun Wan Chan, Shuk Han Cheng, Xueping Chen. Exposure to phthalatesimpaired neurodevelopment through estrogenic effects and induced DNA damage inneurons. Aquatic Toxicology. 2020,222: 105469.

        5. Shisan Xu,Fangjing Xie, Samane Fallah, Fatemeh Babaei, Lina Zhu, Kin Fung Wong, YiminLiang, Rajkumar Ramalingam, Lei Sun, Xin Wang,RobertPlumb, Lee Gethings, Yun Wah Lam, Shuk Han Cheng. Estrogen accelerates heartregeneration by promoting inflammatory responses in zebrafish. Journal of Endocrinology.2020, 245 (1): 39-51.

        6. Xiaojian Li, ShisanXu, Shuk Han Cheng, Dong Sun. Simultaneous localization and Mapping-Basedin vivo navigation control of microparticles. IEEE Transactions onIndustrial Informatics. 2020, 16 (5): 956-2964.

        7. Shisan Xu,Fangjing Xie, Li Tian, Sinai HC Manno, DDS, Francis A. M. Manno III, Shuk HanCheng. Prolonged neutrophil retention in the wound impairs zebrafish heartregeneration after cryoinjury. Fish & Shellfish Immunology. 2019, 94:447-454.

        8. Shisan Xu,Chichi Liu, Fangjing Xie, Li Tian, Sinai HC Manno, DDS, Francis A. M. Manno III,Samane Fallah, Bernd Pelster, Gary Tse, Shuk Han Cheng. Excessive inflammationimpairs heart regeneration in zebrafish breakdance mutant after cryoinjury. Fish& Shellfish Immunology. 2019, 89:117-126.

        9. Shisan Xu,Sarah E. Webb, Terrence Chi Kong Lau, Shuk Han Cheng. Matrix metalloproteinases(MMPs) mediate leukocyte recruitment during the inflammatory phase of zebrafishheart regeneration. Scientific Reports. 2018, 8:7199.